Licensing and collaboration options for research

We offer research licensing and collaboration opportunities to support ethical, evidence-based studies in applied neurophysiology. Academic and clinical researchers can access our validated brain markers and specialized toolkits.

Trusted by Experts, Backed by Science
  • The Applied Neurophysiology Laboratory believes in sharing its markers for research
  • Researchers in acknowledged academic and clinical institutes receive a free license
  • Other researchers, e.g. in commercial organizations, can purchase such a license
  • Rambam will not provide license for markers use, if we consider the use unethical
  • We currently provide two tools for researchers:
    • The task study kit
    • The monitor study kit
The task study kit

This available research tool is used by researchers to evaluate sustained attention (CEI – cognitive effort index) and alertness (TensI – tension index for stress and discomfort). The indices are reported in real-time or could be analyzed offline. The current headset employed by most researchers is the single channel easy to use BrainLink lite, but other headsets are also used. The tool also provides quantitative summary of the indices.

For further information please see the tool’s user manual: 

The monitor study kit

This tool is designed for clinical research mostly in operating rooms or in intensive care units for detection of deterioration or remission of brain function over hours of sample. The current tool contains the BRI (brain reactivity index) marker for orientation, or selective attention, of short responses of the brain to stimuli. Such short responses are preserved in conditions of reduced consciousness (also due to anesthesia), and if they are diminished in these conditions, it implies an acute brain dysfunction.

The current tool also contains the CEIrc (or CEI for reduced consciousness), which is the CEI marker for sustained attention summarized over longer periods in order to detect changes in levels of consciousness, such as awareness. The markers of the monitor study kit could be used in real-time or could be analyzed offline.

Currently the medical EEG system used most often is the single channel easy to use BIS Medtronic, but other medical EEG systems are also used.

Selected publications by other research groups:

– Avirame, K., Gshur, N., Komemi, R., & Lipskaya-Velikovsky, L. (2022). A multimodal approach for the ecological investigation of sustained attention: A pilot study. Frontiers in Human Neuroscience16, 971314.

– Bart, O., & Liberman, L. (2020). Sustained attention in exposure to tactile stimuli among children 4 to 10 years old with and without sensory modulation disorders. The American Journal of Occupational Therapy74(4_Supplement_1), 7411505261p1-7411505261p1.

– Keren, A., Fisher, O., Hamde, A., Tsafrir, S., & Ratzon, N. Z. (2024). Reducing Driving Risk Factors in Adolescents with Attention Deficit Hyperactivity Disorder (ADHD): Insights from EEG and Eye-Tracking Analysis. Sensors24(11), 3319.

– Yogev-Seligmann, G., Krasovsky, T., & Kafri, M. (2022). Compensatory movement strategies differentially affect attention allocation and gait parameters in persons with Parkinson’s disease. Frontiers in Human Neuroscience16, 943047.

If you wish to use the above tools for research, please fill in the form below:

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